The Sigvaris 500 Natural Rubber Stocking is the original gold standard in compression therapy. The stocking has been proven effective through numerous scientific studies and is ideal for patients with more serious indications or long-term therapy. It is manufactured from double-covered, soft, natural rubber to offer the greatest degree of elasticity and durability. The Natural Rubber Stocking can accommodate larger ankle circumferences up to 18" (46cm) and calf circumferences up to 27" (68cm) as a great alternative to custom stockings. The high-stretch knit construction in combination with double-covered yarns makes the product easy to don and remove. The stocking is made of 70% nylon and 30% natural latex rubber.